Alexander The Great
In 334 BC Alexander's army captured the city and following the order of their king, they destroyed whole city except the monumental tomb of king Mausolos. Ada, former queen of Caria regained power and became the queen of Caria.
The city which was destroyed during the siege of Alexander the Great never returned to its former glory. It also suffered during the wars between the generals of Alexander the Great after Alexander's death. The region first fell into hands of Selevkos and passed to Egyptian rule.